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Through her father's art contacts in Italy, Mc Gowan became a child model and appeared in Vogue Bambini and various other Italian magazines.Her parents returned to the United States in 1979 and divorced when Mc Gowan was 10.Celebrities such as Keira Knightly, Carmen Electra, and Virginia Madsen have been known to use the caddies.According to an article in the New York Post, Mc Gowan experienced serious injuries in a car accident early in 2007.

She has also appeared in several major Hollywood films, with leading roles in Scream, Jawbreaker and the Quentin Tarantino/Robert Rodriguez double-feature Grindhouse.For me personally, it's just kind of more instinctive. I fell into it accidentally." Mc Gowan made her first appearance in a Hollywood film with a bit role in the 1992 Pauly Shore comedy Encino Man.Her role in the 1995 black comedy, The Doom Generation, brought her to the attention of film critics, and she received a nomination for "Best Debut Performance" at the 1996 Independent Spirit Awards.She appeared in the critically-acclaimed short Seed, directed by San Francisco-born filmmaker Karin Thayer, in 1997, and played opposite Peter O'Toole in the 1998 film adaptation of the Dean Koontz novel Phantoms.Notably, Mc Gowan also starred in the 1999 comedy/drama Jawbreaker, where she played a high school student who tries to cover up a classmate's murder.

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